Current Science

T. Jacob John ¹, Mukul Das ²

Affiliations
1 439, Civil Supplies Godown Lane, Kamalakshipuram, Vellore 632 002, IN
2 Food, Drugs and Chemical Toxicology Division, CSIR-Indian Institute of Toxicology Research, M. G. Marg, P.O. Box 80, Lucknow 226 001, IN

Abstract

No Abstract.

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B. D. Bhattacharji ¹, Mukul Das ¹

Affiliations
1 CSIR–Indian Institute of Toxicology Research, M.G. Marg, PB No. 80, Lucknow 226 001, IN

Abstract

CSIR-Indian Institute of Toxicology Research (IITR), Lucknow, established on 4 November 1965, is one of the pioneer institutions dealing with toxicology research in the Asia-Pacific region. IITR is the only laboratory in the CSIR family to be awarded the Good Laboratory Practice certification. The five decades of expertise and knowledge base in toxicology research have empowered the Institute to conduct studies in the following niche areas: (i) Food, drug and chemical toxicology, (ii) nanotherapeutics and nanomaterial toxicology, (iii) systems toxicology and health risk assessment, (iv) environmental toxicology, and (v) regulatory toxicology. The highlights of some of the scientific achievements for the year 2014 are described in this article.

Keywords

Health Risk Assessment, Nanoparticles, Nanotherapeutics, Toxicology Research.

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Mukul Das ¹, Somya Asthana ¹, Sheelendra P. Singh ², Sumita Dixit ¹, Anurag Tripathi ¹, T. Jacob John ³

Affiliations
1 Food Toxicology Laboratory, Food, Drug and Chemical Toxicology Group, CSIR-Indian Institute of Toxicology Research, Mahatma Gandhi Marg, P. O. Box 80, Lucknow 226 001, IN
2 Analytical Chemistry Laboratory, Regulatory Toxicology Group, CSIR-Indian Institute of Toxicology Research, Mahatma Gandhi Marg, P. O. Box 80, Lucknow 226 001, IN
3 439, Civil Supplies Godown Lane, Kamalakshipuram, Vellore 632 002, IN

Abstract

No Abstract.

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Mukul Das ¹, Arun Shah ², T. Jacob John ³

Affiliations
1 Food, Drug and Chemical Toxicology Group, CSIR-Indian Institute of Toxicology Research, M. G. Marg, P. O. Box 80, Lucknow 220 661, IN
2 Kejariwal Maternity and Child Hospital, Muzaffarpur 842 001, IN
3 439 Civil Supplies Godown Lane, Kamalakshipuram, Vellore 632 002, IN

Abstract

No Abstract.

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T. Jacob John ¹, G. Arunkumar ², Madan M. Pradhan ³, Mukul Das ⁴

Affiliations
1 No. 439, Civil Supplies Godown Lane, Kamalakshipuram, Vellore 632 002, IN
2 Manipal Centre for Virus Research, Manipal University, Manipal 576 104, IN
3 National Vector Borne Disease Control Programme, Odisha, IN
4 CSIR-Indian Institute of Toxicology Research, 31 Vish Vigyan Bhawan, M. G. Marg, Lucknow 226 001, IN

Abstract

During September through November 2016, some 100 children died due to acute brain disease in Malkangiri district, southern Odisha, India. Most deaths were at first attributed to Japanese encephalitis (JE) due to the following reasons: JE had been reported in Malkangiri district in previous years and diagnostic test for JE was positive in a few children in 2016; JE season is September through November; the vector mosquitoes and amplifying hosts, namely pigs, are prevalent in Malkangiri district. However, a number of cases turned out negative for JE test. Therefore, in the last week of October, the Department of Health, Government of Odisha, constituted a team to investigate the cases of non-JE acute brain disease with high mortality.

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T. Jacob John ¹, Mukul Das ², Abhirup Sarkar ³

Affiliations
1 Formerly atClinical Virology, Christian Medical College, Vellore 632 004, IN
2 Formerly at CSIR-Indian Institute of Toxicology Research, M. G. Marg, Lucknow 226 001, IN
3 Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110 029, IN

Abstract

The paper on ‘Determination of tolerable dose of litchi fruit’ by Tripathi et al.¹ confirms the safety of litchi in mice, and by extrapolation, in normal people. In-deed litchi has never been alleged to be unsafe in normal people.

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